Which instruction restricts intelligence personnel from collecting information on U.S. persons?

DOD 5240.1-R is the instruction that specifically restricts intelligence personnel from collecting information on U.S. persons. This regulation is part of the Department of Defense's guidelines to ensure the protection of individual rights and privacy in the context of intelligence operations. The instruction establishes policies and procedures to limit the collection of data on U.S. citizens, residents, or domestic entities to avoid invasive surveillance practices that could violate civil liberties.

Understanding this framework is crucial for personnel in positions involving intelligence to ensure compliance with legal and ethical standards while conducting operations. It emphasizes the need for safeguards in domestic intelligence activities and reflects a balance between national security requirements and the constitutional rights of individuals.